Mild cognitive impairment (MCI) is a transitional stage between normal aging and Alzheimer’s disease (AD), with a high risk of converting to AD.We propose a classification framework cestrum orange peel with a data augment method to identify MCI converter (MCI-C) and MCI non-converter (MCI-NC).Resting-state functional magnetic resonance images (rs-fMRI) from Alzheimer’s Disease Neuroimaging Initiative (ADNI) are processed as augmented resting-state functional connectivity by staggered sliding window (SSW) method proposed by us under Human Connectome Project (HCP) multi-modal parcellation.The HCP brain atlas provides a more detailed cortical parcellation of the brain, allowing for more precise localization of brain regions related to utopia hoodie brown MCI and AD.
Finally, the framework archive 88% accuracy in the task of identifying MCI-C.46 brain regions are suggested as potential MCI-to-AD biomarkers.